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end point of death

Clinical endpoint - Wikipedia, the free encyclopedia
A cancer study may be powered for overall survival, usually indicating time until death from any cause, or disease specific survival, where the endpoint is death .
http://en.wikipedia.org/wiki/Clinical_endpoint

Surrogate endpoint - Wikipedia, the free encyclopedia
Surrogate markers are used when the primary endpoint is undesired (e.g., death) , or when the number of events is very small, thus making it impractical to .
http://en.wikipedia.org/wiki/Surrogate_endpoint

GUIDELINES ON DEATH AS AN ENDPOINT
CHUA Appendix VI. SUNY UPSTATE MEDICAL UNIVERSITY. Committee for the Humane Use of Animals (CHUA). GUIDELINES ON DEATH AS AN ENDPOINT .
http://www.upstate.edu/dlar/chua/guidedeath.pdf

Specific Programs at end point of death:

GUIDELINES FOR DEATH AS AN ENDPOINT
Island discourages the use of death as an endpoint and instead encourages the use of alternative endpoints. Some examples of alternative endpoints include .
http://www.uri.edu/research/tro/about/IACUC/endpoint.pdf


COPD
Pneumonia
Respiratory failure
ALS
Guillain-Barre

Death As an Endpoint - The Body
In clinical trials of HIV drugs, the term 'endpoint' is often misunderstood as meaning the end of the trial or the end of a participant's enrollment in ...
http://www.thebody.com/content/art13241.html


Infectious disease
Congestive heart failure
Uncontrolled diabetes
Cardiovascular diseases
Prolonged surgical recovery
Cancer
Sepsis
Multi-system complications
Malnutrition
Degenerative disease

AWIC Newsletter: Defining an Acceptable Endpoint in Invasive ...
Types of Studies Where Death of the Animal May be the Endpoint .
http://www.nal.usda.gov/awic/newsletters/v6n1/6n1olfer.htm


Post-trauma CVA (Stroke)
Spinal cord injury
Cerebral hemorrhage
Neurologic complications
Orthopedic complications
Aneurysm or head injury
Anoxic brain injury
Joint replacement

Death as an endpoint - Department of Primary Industries
Nov 14, 2011 . Death as an end-point and other regulated high impact procedures. "Death as an end-point" (DAEP) Scientific Procedures are rare, potentially .
http://www.dpi.vic.gov.au/agriculture/science-and-research/animals-used-research-and-teaching/licensing-of-scientific-procedures/death-as-an-endpoint


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Mississippi State University IACUC Standard Operating Procedure
IACUC's policy regarding investigators using death as an endpoint in . euthanasia in death as an endpoint experiments before the actual death of the animals if .
http://www.lar.msstate.edu/pdf/Death%20as%20an%20End%20Point.pdf



Death as an Endpoint
Death as an Endpoint. IACUC Authorized Signature. 1.0 Introduction. 1.1 Death or moribundity is not an acceptable study endpoint. Every effort must be made to .
http://www.isu.edu/anmlcare/docs/ISUP003%20Death%20as%20an%20Endpoint.pdf

Death as an Endpoint › Animal Care Committee › University of ...
It is imperative to understand what "Death as an Endpoint" is. It is the natural . Euthanasia of animals is NOT a death as an endpoint activity. The use of death as .
http://acc.uchc.edu/faq/endpoint.html

POLICY ON USE OF DEATH AS AN ENDPOINT IN ANIMAL ...
the IACUC for using death of animals as the experimental endpoint. IACUC . Scientific justification for using death as an endpoint must be provided in writing as .
http://www.nus.edu.sg/iacuc/files/Policy%20on%20Death%20as%20an%20Endpoint.pdf

The 'natural' endpoint of dementia: death from cachexia or ...
The 'natural' endpoint of dementia: death from cachexia or dehydration following palliative care? Koopmans RT, van der Sterren KJ, van der Steen JT.
http://www.ncbi.nlm.nih.gov/pubmed/17022107

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End points in the analysis of breast cancer survival: Relapse versus ...
Dec 1, 2005 . The end point of death from tumor generally is accepted as the most . If the end point used for actuarial analysis is death from breast cancer, .
http://linkinghub.elsevier.com/retrieve/pii/S0039606098701205

The Problem With Composite End Points in Cardiovascular Studies ...
Thus, when TVR was added to the safety end point of death, MI, or ST, the number of incident events nearly doubled. When any repeat revascularization was .
http://content.onlinejacc.org/cgi/content/full/51/7/701

Table: Primary endpoint (cardiovascular death, myocardial infarction ...
Primary endpoint (cardiovascular death, myocardial infarction, or stroke) and myocardial infarction (clopidogrel vs prasugrel) according to different definitions of .
http://www.thelancet.com/journals/lancet/article/PIIS0140673609610229/table?tableid=tbl1&tableidtype=table_id§ionType=lightBlue

Read more about the end point of death family

Medical Director

DEATH AS AN ENDPOINT
Background: The routine use of death as an endpoint should be discouraged. Endpoints other than death must always be considered and should be used .
http://www.ohsu.edu/xd/about/services/integrity/policies/loader.cfm?csModule=security/getfile&pageid=2038567



RATS Online Help
Death as an Endpoint . Strategies for Reducing Animal Numbers in Death- endpoint Experiments. The traditional LD50 experiment to measure toxicity is widely .
http://www.research.ucla.edu/rats_help/manual/PoliciesAndGuidelines/PoliciesGuidelines_EuthanasiaEndpoint.asp



Is Cell Death a Critical End Point for Anticancer Therapies or Is ...
Dec 15, 2007 . Abstract. Since the discovery of conventional chemotherapy and the development of new target-based agents, the importance of cytostasis in .
http://clincancerres.aacrjournals.org/content/13/24/7280.full



Death is Not the End | The Point Magazine
David Foster Wallace, who hanged himself in his home last September, wrote about authenticity, self-consciousness and the pursuit of happiness in America.
http://www.thepointmag.com/2009/essays/death-is-not-the-end

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